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Tramadol is a prescription medication used to treat moderate to moderately severe pain. It is classified as a centrally acting opioid analgesic and works by binding to opioid receptors in the brain and spinal cord while also inhibiting the reuptake of norepinephrine and serotonin, which enhances its pain-relieving effects. Tramadol is often prescribed for acute pain after surgery, chronic pain conditions, or when other pain medications are insufficient.

The typical dosage of Tramadol varies depending on the formulation and patient factors. For immediate-release tablets, adults are commonly prescribed 50 mg every 4 to 6 hours as needed, with a maximum daily dose of 400 mg. Extended-release formulations are used for around-the-clock pain management and are usually taken once or twice daily, with careful monitoring. Dosage adjustments are necessary for elderly patients, or those with kidney or liver impairment, and Tramadol should never be combined with other CNS depressants without medical supervision.

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